Amoxicillin potassium clavulanate is a drug that is a combination of amoxicillin and potassium clavulanate as per the amoxicillin clav manufacturer in India. It is considered a mainstay antibiotic in emergency conditions and even in primary care offices throughout the nation.
As per the pharma manufacturers in India, Amoxicillin is considered to be an extended spectrum of β-lactam antibiotics whose structure is similar to Ampicillin. According to medical experts, the resistance to amoxicillin is due to β-lactamase enzymes which are usually found in resistant strains. On the other hand, the potassium clavulanate is produced by the fermentation of Streptomyces clavuligurus which is a β-lactamase inhibitor. This can irreversibly inactivate the β-lactamase enzymes. Furthermore, according to the information given by medicine manufacturers, the combination of amoxicillin: potassium clavulanate in the ratio of 2:1 is freely soluble in water.
The clavulanic acid is considered to be particularly active against the clinically important plasmid-mediated β-lactamases which are responsible for the transferred drug resistance to penicillin and cephalosporins. The doctors and other medical practitioners usually prescribe amoxicillin and potassium India for the treatment of bacterial infections.
The spectrum of Amoxicillin Clavulanate
Amoxicillin is said to be a penicillin derivative which shows similar activity against gram-positive and gram-negative bacteria. As per the information given by amoxicillin clav manufacturer in India, this drug shows activity against bacteria namely Moraxella catarrhalis, Enterococcus species, Haemophilus influenzae, Corynebacterium diphtheria, Corynebacterium diphtheria, Listeria monocytogenes, Streptococcus species, Salmonella spp, Borrelia species and Shigella spp.
Furthermore, the pharma manufacturers in India say the addition of clavulanic acid increases the medicine’s spectrum to include all beta-lactamase-producing strains and broadens the coverage to include methicillin sensitive Staphylococcus aureus (MSSA), Neisseria species, Proteus species, Pasteurella multocida, and Capnocytophagacanimorsus, among others.
What is this drug used for?
According to available information from the medicine manufacturers in India, this medicine has FDA-approved indications for the treatment of aspiration pneumonia, skin and soft tissue infections, acute bacterial rhinosinusitis, acute otitis media, Community-acquired pneumonia and urinary tract infections. The combination of amoxicillin and potassium clavulanate is also used for the treatment of wounds or infections that are not mentioned on its label. As per the medical data, this medicine is used for curing impetigo, Peritonsillar cellulitis/abscess, Treatment of human or animal bite wounds, Diabetic foot infections, Group A streptococcal infections, acute exacerbations of chronic obstructive pulmonary disease and bronchiectasis, and Odontogenic infections.
How is the drug given?
According to data given by the amoxicillin clav manufacturer in India, this tablet is available only in oral form. Like other antibacterial antibiotics, it is to be taken at regular intervals. The doctor usually prescribes it twice or thrice a day to destroy the organism completely. The medicine is available in different flavours such as apple, banana cream, bubble gum, cherry, or even watermelon for better palatability, particularly in the pediatric population.
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