Amoxicillin and clavulanic acid, also known as amoxicillin and clav, is a combination antibiotic medication commonly prescribed in India to treat a range of bacterial infections. Amoxicillin is a penicillin-type antibiotic, while clavulanic acid helps to prevent bacterial resistance to the antibiotic. This article aims to provide a comprehensive guide to amoxicillin and clav in India, including its uses, dosage, side effects, precautions, and interactions.

Uses of Amoxicillin and Clav

Amoxicillin and clav is commonly used to treat various types of bacterial infections, including:

  • Upper respiratory tract infections such as sinusitis, pharyngitis, and tonsillitis
  • Lower respiratory tract infections such as pneumonia, bronchitis, and exacerbations of chronic obstructive pulmonary disease (COPD)
  • Urinary tract infections such as cystitis and pyelonephritis
  • Skin and soft tissue infections such as cellulitis and impetigo
  • Dental infections such as dental abscesses and periodontitis

Dosage of Amoxicillin and Clav

The dosage of amoxicillin and clav in India may vary depending on the type and severity of the infection, age and weight of the patient, and other factors such as kidney function. It is important to follow the prescribed dosage and duration of treatment to ensure effective treatment and prevent antibiotic resistance.

The usual dosage of amoxicillin and clav for adults and children weighing more than 40 kg is 625 mg or 1 g every 8 hours, or 875 mg every 12 hours. For children weighing less than 40 kg, the dosage is calculated based on their weight and age.

Side Effects of Amoxicillin and Clav

Like all antibiotics, amoxicillin and clav may cause side effects, although not everyone experiences them. The most common side effects of amoxicillin and clav in India include:

  • Nausea, vomiting, and diarrhea
  • Skin rash, itching, and hives
  • Headache and dizziness
  • Abdominal pain and cramps

In rare cases, amoxicillin and clav may cause severe allergic reactions such as anaphylaxis, which can be life-threatening. If you experience any signs of an allergic reaction such as difficulty breathing, swelling of the face or throat, or severe rash, seek medical attention immediately.

Precautions and Interactions of Amoxicillin and Clav

Amoxicillin and clav may interact with other medications or medical conditions, so it is important to inform your doctor of any other medications you are taking or medical conditions you have, such as:

  • Allergies to penicillin or other antibiotics
  • Liver or kidney disease
  • Blood disorders such as anemia or bleeding disorders
  • Pregnancy or breastfeeding

Amoxicillin and clav may also interact with certain medications such as:

  • Methotrexate, a medication used to treat cancer and autoimmune diseases
  • Probenecid, a medication used to treat gout
  • Warfarin, a medication used to prevent blood clots

It is important to follow your doctor’s instructions and inform them of any changes in your health or medication regimen.


Amoxicillin and clavulanic acid is a commonly prescribed combination antibiotic medication in India for the treatment of bacterial infections. While it is generally safe and effective, it is important to follow the prescribed dosage and duration of treatment, and inform your doctor of any other medications or medical conditions you have. If you experience any side effects or signs of an allergic reaction, seek medical attention immediately.

Why Medicef Pharma?

Medicef Pharma is a pharmaceutical manufacturing company based in India. They specialize in producing high-quality generic medicines, including antibiotics, anti-inflammatory drugs, and more. As one of the leading pharma manufacturers in India, Medicef Pharma has a strong commitment to providing affordable and accessible healthcare solutions for people around the world. Their state-of-the-art manufacturing facilities, strict quality control measures, and experienced team of professionals ensure that their products are safe, effective, and of the highest quality. Whether you’re a healthcare professional or a patient, you can trust Medicef Pharma to provide you with reliable and affordable medications.

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